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William J. Stekiel, Ph.D.
Professor
Phone: (414) 456-8528 
Email: wstekiel@mcw.edu
B.S. Marquette University, 1950
Ph.D. Biophysics, Johns Hopkins University, 1957
USPHS Postdoctoral Fellow Physiology, Marquette University School of Medicine, 1957-1959
Research areas: Cardiovascular Physiology
  Molecular & Cellular Physiology

Upon retirement from full-time employment in July of 1993, I have continued my academic activities on a part-time basis with a faculty appointment as a full time professional equivalent in the Department of Physiology. My current teaching activities include lectures and lab instruction in the basic medical physiology course, lectures in the electrophysiology section of the basic integrated neuroscience course for medical and graduate students, and participation as one of the moderators in a physiology graduate course (Cell and Tissue Transport Mechanisms). I have also initiated a new research interest in collaboration with colleagues in the Department of Anesthesiology. Its overall goal is to improve our understanding of the mechanisms by which clinically relevant concentrations of volatile anesthetics inhibit the extrinsic neural and intrinsic vascular cell regulatory mechanisms that control peripheral vascular resistance.  

Recent Publications:
Stekiel TA, Contney SJ, Bosnjak ZJ, Kampine JP, Roman RJ, and Stekiel WJ. Chromosomal substitution-dependent differences in cardiovascular responses to sodium pentobarbital. Anesthesia & Analgesia. 2005 (Accepted for publication).

Stekiel TA, Contney SJ, Bosnjak ZJ, Kampine JP, Roman RJ, and Stekiel WJ. Reversal of minimum alveolar concentrations of volatile anesthetics by chromosomal substitution. Anesthesiology 2004; 101(3):796-798.


Stekiel TA, Contney SJ, Kokita N, Bosnjak ZJ, Kampine JP, and Stekiel WJ. Mechanisms of isoflurane-mediated hyperpolarization of vascular smooth muscle in chronically hypertensive and normotensive conditions. Anesthesiology 2001; 94(3):496-506.

Stekiel TA, Kokita N, Yamazaki M, Bosnjak ZJ, Kampine JP, and Stekiel WJ. Effect of isoflurane on in situ vascular smooth muscle transmembrane potential in spontaneous hypertension. Anesthesiology 1999; 91(1):207-214.

Kokita N, Stekiel TA, Yamazaki M, Bosnjak ZJ, Kampine JP, and Stekiel WJ. Potassium channel-mediated hyperpolarization of mesenteric vascular smooth muscle by isoflurane. Anesthesiology 1999; 90(3):779-788.
© 2005 Medical College of Wisconsin

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