All seminars are 8:30 am – 9:30 am in the Physiology Conference Room (BSB 576) unless otherwise noted. 

July 2008

• July  2 -  Michael Michalkiewicz, Ph.D. - Epigenetics of hypertension and renal disease
• July  9 -  Aaron Polichnowski - Mechanisms of renal injury in hypertensive models with altered angiotensin II and Nitric Oxide
• July 16 - James Stockand, Ph.D. - Hypertension in P2Y2 receptor-deficient mice is caused by constitutive activation of ENaC
• July 23 - Allen W. Cowley, Jr., Ph.D. - Mechanisms of renal medullary oxidative stress in salt-sensitive hypertension
• July 30 - Lucas Hart - Cerebral cortex blood flow responses in skilled behavior and motor learning

June 2008

• June  4 -  Daniel Brozoski - The role of endocannabinoids in the central control of the baroreflex in hypertensive and normotensive rats
• June 11 - Ashraf El-Meanawy M.D., Ph.D. - Oligonephronia in the Oligosyndactyly mouse
• June 18 - No Seminar
• June 25 - Josh Bonis - Modulation of the pontine respiratory group alters breathing and sleep

May 2008

• May  7 -  Diane Munzenmaier, Ph.D. - Angiotensins and vascular growth: the controversy continues
• May 12 - JJ Smith Lecture, Dr. Eric O. Feigl - Control of coronary blood flow during exercise (Why we don't die when we walk up the stairs)
• May 14 - Ronald M. Harper, Ph.D. - Imaging of brain structure in sleep-disordered breathing
• May 20 - Master's Thesis, Matthew Brown - Vascular remodeling in a rat model of unilateral pulmonary artery hypoplasia
• May 21 - Jordan Miller, Ph.D. - Oxidative stress in calcific aortic valvular stenosis
• May 27 - Dissertation Defense, Alison Kriegel - Substitution of Brown Norway chromosome 16 preserves cardiac function with aging in a salt-sensitive Dahl consomic rat
• May 28 - Ellis Avner, M.D. - New insights into cellular pathophysiology of polycystic kidney disease

April 2008

• April  2 -  Jan Williams, Ph.D. - The progression of renal disease in the Dahl S rat vs. the FHH rat: Who's your money on?
• April  9 -  No Seminar
• April 14 - Nader Abraham, Ph.D. - Functional expression of heme oxygenase-stem cells in obesity and metabolic syndrome
• April 15 - Peter Hunter, Ph.D., FRS - Multi-scale modeling and computational physiology
• April 16 - Michael Harrison, Dissertation Defense - The comparative genetics of Phosducin, a novel candidate gene for hypertension
• April 17 - Lutz Hein, MD - Adrenergic signaling at the interface between neuronal and cardiovascular systems
• April 23 - Robin L. Davisson, Ph.D. - Student Choice Speaker - Physiological genomic analysis of cardiovascular disease
• April 30 - David Harder, Ph.D. - To Be Announced

March 2008

• March  4 -  Raymond C. Koehler, Ph.D. - Mechanisms of neurovascular coupling
• March  5 -  Kathryn Dunn, Dissertation Defense - The role of 20-HETE in ischemic stroke sensitivity and cerebral vascular oxidative stress in spontaneous hypertension
• March 12 - Simon Twigger, Ph.D. - Seven bioinformatics secrets you need to know
• March 19 - Katie Krause, Dissertation Defense - The role of the pre-Botzinger Complex in respiratory rhythmogenesis and chemosensitivity during physiologic conditions
• March 26 - Alexander Starushchenko, Ph.D. - Acute regulation of the Epithelial Na+ Channel by P13-kinase signaling

February 2008

• Feb.  6 -  Anthony Hudetz, DBM, Ph.D. - Neural correlates of anesthesia
• Feb. 13 - Gabor Raffai, Ph.D. - Adaptation of the cardiovasculary system to gravitational loading: systemic hemodynamic and regional vascular responses to acute and chronic orthostasis
• Feb. 20 - Jeanne Seagard, Ph.D. - Endocannabinoid modulation of baroreflex control
• Feb. 27 - Kirk Pritchard, Ph.D. - Matrix instability and impaired angiogenesis in tight skin mice - a murine model for systemic sclerosis

January 2008

• Jan.  2 -  No Seminar
• Jan.  9 -  Philip Clifford, Ph.D. - Reedforward skeletal muscle vasodilation at the onset of exercise.
• Jan. 16 - Daniel Beard, Ph.D. - Simulation and analysis of coronary oxygen transport and cardiac energy metabolism.
• Jan. 23 - David Rector, Ph.D. - High frequency oscillations (200-600Hz) and their role in sensory processing.
• Jan. 30 - David Mattson, Ph.D. - Protein-sensitive hypertension and renal disease in Dahl SS rats.

December 2007

• Dec. 5     -  No Seminar
• Dec. 12   -  Zeljko Bosnjak, Ph.D. - Protection against ischemia and reperfusion injury
• Dec. 19   -  Yong Liu, Ph.D. - 11B-hydroxysteroid dehydrogenase 1: from adipogenesis to salt-sensitive hypertension
• Dec. 26   -  No Seminar

November 2007

• Nov. 7     -  Julie Freed, Disseration Defense - Proteomic analysis of shear stress-mediated protection from apoptosis in endothelial cells
• Nov. 14   -  Paul O'Connor, Ph.D. - Oxidative stress in the renal medulla of salt-sensitive rats
• Nov. 21   -  Thanksgiving Week - No Seminar
• Nov. 27  -   Kelly Duffy, Dissertation Defense - Functional genetic analysis of pathogenic chromosomal copy number variation in Down syndrome and Proteus syndrome
• Nov. 28   -  Bradford C. Berk, MD, Ph.D. - Genetics of vascular remodeling

October 2007

• Oct. 3    -  Andrew S. Greene, Ph.D. - Recent progress in the Greene Lab
• Oct. 10  -  Marc Chevalier, Ph.D. - Body rhythms linked to ion channel activity: focus on epilepsy disorders
• Oct. 17  -  Jean F. Liard, MD, Ph.D. - Bumps on the translational highway
• Oct. 24  -  Satarupa Das, Grad Student - Role of immune cells in the development of hypertension and kidney disease
•                  Carmen De Miguel, Grad Student - Effects of L-Arginine infusion on Angiotensin II-induced hypertension
• Oct. 31  -  Howard Jacob, Ph.D. - Linking the Framingham Heart Study to the Program in Genomic Applications

September 2007

• Sept. 12  -  Hartmut Weiler, Ph.D. - Protein C Pathway in the Treatment and Pathogenesis of Sepsis
• Sept. 19 -  Lucas Hart - The role of the neurovascular unit in learning
• Sept. 26 -  Michael Olivier, Ph.D. - Human functional Disease Genetics: The trials and Tribulations of NOT Working with Rats

August 2007

• Aug. 1   -  Allen Cowley, Jr. - Hypertension and pressure-natriuresis in theory and practice
• Aug. 8   -  Graduate Student Retreat
• Aug. 15 -  Aaron Polichnowski - Hypertension-induced renal damage
• Aug. 22 -  Daniel Brozoski - The role of endocannabinoids in the central control of the baroreflex
• Aug. 29 -  Domagoj Mladinov - Further understanding the mechanism of hypertension - analysis of eNOS promoter
• Aug. 29 -  Talha Akbulut - The role of cytochrome P450 following ischemia-reperfusion injury in the rat kidney

July 2007

• July 4  - Holiday
• July 11 - Josh Bonis - The pons: where do we go, how do we get there, and what does it do for breathing
• July 20 - Steven R. Goldsmith, MD - Vasopressin antagonism in heart failure and hyponatremia: theory and current practice
• July 25 - Alison Kriegel - Characterization of idiopathic left ventricular hypertrophy and impaired cardiac function in the SS-16BN/Mcwi consomic rat

June 2007

• June 6  - Kelly Duffy - Somatic partial chromosome 11 duplication in patients with Proteus syndrome
• June 14 - Kimberly Pechman, Dissertation Defense - The long term effects of altered structure and function following acute renal failure
• June 20 - Katie Dunn - The role of 20-HETE in ischemic stroke and cerebral vascular dysfunction in the stroke prone rat
• June 27- Katie Krause - The pre-Botzinger complex may not be the sole determinant of respiratory rhythm

May 2007

• May 2   - No Seminar
• May 9   - Mingyu Liang, Ph.D. - MicroRNA
• May 16 - Thomas Feroah, Ph.D. - Assessing novel and circadian movement behavior in parental and ENU knockout inbred strains of rats
• May 23 - Edward Smith, Ph.D. - Fine-mapping a human QTL associated with the lipid profile
• May 30 - Tetsuro Wakatsuki, Ph.D. - To Be Determined

April 2007

• April 4   - Xujing Wang, Ph.D. - Network modeling of gene expression data
• April 11 - Hubert Forster, Ph.D. - Muscle activation patterns and neural mechanisms regulating multiple behaviors utilizing the respiratory muscles
• April 18 - Michael Michalkiewicz, DVM, Ph.D. - Validation of a candidate disease gene with inclusion of epigenomic tools
• April 24 - Jeffrey Eckert, Grad Student Dissertation Defense - The role of protein tyrosine phosphatase 1 beta sequence variants in human obesity
• April 25 - Donald Bowden, Ph.D. - Genetics studies of diabetes, metabolic dysregulation, and their complications in diverse human populations
• April 26 - Kevin Campbell, Ph.D. - Student Choice Seminar - Maintenance of cell membrane integrity and the pathogenesis of muscular dystrophy, 3:30 HRC Auditorium

March 2007

• March 7 - Andrew Tryba, Ph.D. - Mechanisms of rhythm generation in neocortical epilepsy
• March 14 - Melinda Dwinell, Ph.D. - Who's on first? Deciphering chromosome1 using consomic rats
• March 21 - Scott McEwen, Grad Student Dissertation Defense - The role of AT-1 receptor signaling to restore cerebrovascular relaxation mechanisms
• March 22 - Abraham P. Provoost, Ph.D. - Physiological genomics of renal damage and blood pressure in the FHH rat
• March 29 - Jasna Marinovic, Grad Student Dissertation Defense - The role of sarcolemmal KATP channel in cardiac preconditioning and apoptosis
• March 30 - Marko Ljubkovic, Grad Student Dissertation Defense - Cardiomyocyte resistance to injury can be enhanced by modulation of mitochondrial K+ homeostasis

February 2007

Note Thursday Seminar

• Feb. 7 - Frank Park, Ph.D. - The nuts and bolts about lentiviral vectors
• Feb. 14 - Rajesh Khanna, Ph.D. - Ion channel trafficking: from molecule to malady
• Feb. 22 - Michael Garrett, Ph.D. - Searching for the molecular basis of renal disease in the Dahl salt-sensitive rat: linkage analysis, congenic strains, and fine-mapping using recombinant progeny testing
• Feb. 28 - Kalyan Vinnakota, Ph.D. - pH dynamics, glycogenolysis and phosphoenergetics in isolated cell free reconstituted systems and in mouse skeletal muscle

January 2007

• Jan. 3  -  No Seminar
• Jan. 10 - Julian Lombard, Ph.D. - Role of Angiotensin II in regulating vascular relaxation mechanisms: more new verses to an old song
• Jan. 17 - No Seminar
• Jan. 24 - Simon Twigger, Ph.D. - Annotating the List - bioinformatic approaches to experimental data annotation
• Jan. 31 - Tatjana Adamovic, Ph.D. - Identification and characterization of cancer genes in hormone-dependent tumors: molecular genetic analysis  in rat models of endometrial and mammary cancer

December 2006

• Dec. 6  -  Bernardo Lopez-Cano, Ph.D. - QTL on chromosome 1 for autoregulation of RBF: what does it mean for ESRD?
• Dec. 13 - Jeanette Vasquez Vivar, Ph.D. - Tetrahydrobiopterin in the regulation of vascular oxidative stress
• Dec. 20 - Daniel Beard, Ph.D. - Computational Systems Biology
• Dec. 27 - No Seminar

November 2006

• Nov. 1 -  No Seminar
• Nov. 8 -  CANCELLED - Hannah Kinney, M.D. Associate Professor, Dept. of Neuroscience, Children's Hospital Boston
• Nov. 9  -  Kleber Franchini, MD, Ph.D., Sao Paulo, Brazil
• Nov. 17 - Robert T. Tranquillo, Ph.D., Professor and Head, University of Minnesota
• Nov. 22 - Aaron Polichnowski, Grad. Student, Physiology
• Nov. 29 - Edmund J. Crampin, Ph.D., Senior Lecturer, Auckland University, New Zealand

October 2006

• Oct. 4 - Daniel Brozoski, Graduate Student
• Oct. 11 - Niloofar Tabatabai, Ph.D., Assistant Professor
• Oct. 18 - Greg McQuestion, Manager, Information Systems
• Oct. 25 - Robert C. Molthen, Ph.D., Assistant Professor

September 2006

• Sept 6 - Julie Freed, Graduate Student
• Sept 13 - Katie Dunn, Graduate Student
• Sept 20 - Aron Geurts, Ph.D.
• Sept 27 - Marko Ljubkovic, Graduate Student

August 2006

• Aug 2 - Anil Bidani, M.D. - Pathophysiology of BP transmission and hypertensive kidney damage.
• Aug 9 - Graduate Student Retreat.
• Aug 16 - Kelly Duffy - Analysis of chromosomal rearrangements in children with multiple congenital anomalies and proteus syndrome using       affymetrix 100K arrays.
• Aug 22 - Pontus Persson, Ph.D. - The renin angiotensin system in the control of blood pressure: subcellular to integrative system analysis.
• Aug 30 - Katie Krause - Is there only one respiratory rhythm generator?

July 2006

• July 5 - Jasna Marinovic - The Role of Sarcolemmal KATP Channel in Cardiac Preconditioning and Apoptosis.
• July 12 - Debebe Gebremedhin - Sensing of Hypoxia by Ca2+ -Activated K+ Channels in the Brain.
• July 19 - Kimberly Spurgeon - The Long Term Effects of Microvascular Rarefaction Following Acute Renal Failure.
• July 26 - Scott McEwen - Characterizing the Role of AT-1 Receptor Signaling in Restoring Cerebral Vasodilator Responses During High Salt Intake.
• July 31 - Jo Rae Wright, Ph.D. - Student Choice Speaker from Duke University

June 2006

• June 7 - Michael Harrison - The genetics of hypertension in French-Canadians: focusing on the phosducin gene.
• June 14 - CANCELLED
• June 21 - Jeffrey Eckert - PTPN1 Haplotypes: do they make us obese?
• June 28 - Paul Martino - Dissertation Defense - The role of the cerebellum in the control of breathing.

May 2006

• May 3 - Diane Munzenmaier, Ph.D. - Angiotensin receptor blockade and cerebral angiogenesis
• May 10 - Micheline Resende, Ph.D. - Role of endothelial cell apoptosis in the regulation of skeletal muscle angiogenesis during high and low      salt intake
• May 17 - Jiaxuan Zhu, Ph.D. - High salt diet induced impaired vasodilation and the effect of superoxide and angiotensin II supression
• May 24 - Shougang Zhuang, MD - Epidermal growth factor receptor: a critical regulator of renal epithelial cell regeneration
• May 31 - Farhan Rizvi, Ph.D. - Characterization of a novel mouse obesity phenotype caused by interspecific hybridization

April 2006

• April 19 - Thom R. Feroah, Ph.D. - Circadian sleep patterns in inbred rats.
• April 26 - Paul Brookes, Ph.D. - Mitochondrial membrane potential as a common end-point in cardioprotection

March 2006

• March 1 - Melinda Dwinell, Ph.D. - Consomic rat models for respiratory control
• March 8 - David F. Stowe, M.D., Ph.D. - Why do mitochondria make reactive oxygen species if they are so bad?
• March 15 - CANCELLED - Catherine L. Coulter, Ph.D. - A central role for glucocorticoids in the early origins of adult disease?
• March 22 - Matthew Petersen, Graduate Student Disseration Defense - The effect of dietary salt intake of skeletal muscle angiogenesis
• March 23 - Enis Novalija, Graduate Student Disseration Defense - Role of reactive oxygen species in anesthetic preconditioning
• March 24 - Norman Taylor - Graduate Student Disseration Defense - The role of reactive oxygen species in the regulation of renal medullary function in salt-sensitive hypertension
• March 24 - Artur Rangel Filho - Physiological genomics of the Rf-2 locus
• March 27 - Nancy Schlick, Graduate Student Disseration Defense - Tenetic and Physiologic characterization of (diabetic) nephropathy in the Type II diabetic nephropathy (T2DN) rat
• March 29 - Michelle Lutz, Graduate Student Disseration Defense - Studies on the interaction between two loci, Rf-1 and Rf-4, in hypertension-induced renal failure

February 2006

• Feb. 1 - Edwin N. Lightfoot, Ph.D. - Mass and heat transfer in 2D gels
• Feb. 8 - Anne Kwitek, Ph.D. - Genetics of complex disease: Why be comparative?
• Feb. 15 - Howard Jacob, Ph.D. - Genetics as a glue for translational medicine
• Feb. 22 - Gale Davy, Executive Director of WABRE - Threats and challenges for biomedical research

January 2006

• Jan  4 - J. Pablo Marquez, Ph.D. - The mechanics of bio-artificial tissue constructs
• Jan 11 - David Wilcox, Ph.D. - Gene therapy for inherited bleeding disorders
• Jan 18 - Martin Hessner, Ph.D. - A functional role for mast cells in BB rat T1DM
• Jan 25 - Marshall Dunning, III, Ph.D. - Exhaled breath condensate in lung disease

December 2005

• Dec. 7:   Marko Ljubkovic - Targeted expression of K+ channel in mitochondria confers cellular protection.
• Dec. 14: Jeroen A.L. Jeneson, Ph.D. from the Netherlands - The energy-balancing act of mitochondria in striated muscles: from metabolome to function via dynamic measurements and computational models.