All seminars are 8:30 am – 9:30 am in the Physiology Conference Room (BSB 576) unless otherwise noted. 

November 2009

• Nov. 4- Julian Lombard, Ph.D., Professor, Physiology MCW- Protective Effect of Physiological Angiotensin II Levels to Preserve Endothelial Function and Maintain Vascular Relaxation: Implications for Salt-Sensitive Hypertension.
• Nov. 11- Gabor Raffai, Ph.D., Postdoctoral Fellow, Physiology MCW- Biomechanical Properties of Human Intracranial Aneurysms: What leads to their rupture?
• Nov. 18- Faiza Ben Mabrouk, Ph.D., Postdoctoral Fellow, Physiology MCW- Neuromodulation of rhythmic motor activities and intrinsic bursting properties: from locomotion to respiration.
• Nov. 19- Filip Sedlic- Dissertation Defense- The role of reactive oxygen species and partial mitochondrial depolarization in cardiac preconditioning.
• Nov. 25- NO SEMINAR

October 2009

• Oct. 7- Jefferson Frisbee, Ph.D, Associate Professor of Physiology and Pharmacology, West Virginia University, Microvascular Perfusion and Peripheral Vascular Disease: A Shift in Fractal Distribution Patterns?
• Oct. 14- Ranjan Dash, Ph.D., Associate Professor of Physiology, Biotechnology and Bioengineering, MCW- Mechanism-oriented computational modeling of mitochondrial bioenergetics and cation handling.
• Oct. 21- Mark Shapiro, Ph.D., Associate Professor of Physiology, University of San Antonio- Receptor-specific modulation of neuronal ion channels.
• Oct. 28- Terry Vanden Hoek, M.D., Associate Professor of Medicine, University of Chicago- Role of the Survival Kinase Akt in Resuscitation from Sudden Death.

September 2009

• Sept. 2 - Satarupa Das, Graduate Student - The anti-hypertensive role of L-Arginine on Angiotensin II induced hypertension in rats
• Sept. 9 - Daniel Beard, Associate Professor - Strong inference for systems biology
• Sept. 16 - Research Day, Christine E. Seidman, MD. - Cardiac Hypertrophy: Lessons from Mutations and Models
• Sept. 22 - Takefumi Mori, MD, PhD, Associate Professor - Paradigm shift of anti-aging from the ancient may explain the pathogenesis of chronic kidney disease
• Sept. 30 - Frank Park, PhD, Associate Professor - Receptor-independent G protein regulator modulates proliferation in PKD

August 2009

• August 5- Graduate Student Retreat Day
• August 12- Domagoj Mladinov, Graduate Student- MicroRNA in nephron segmental physiology.
• August 19- Dora Hargitai M.D., Semmelweis University- The Effect of Purinergic Receptor Activation and the Extracellular Ionic Enviroment on Calcium Entry in Human Airway Epithelial Cells.
• August 26- Ogugua Anene-Maidoh, Graduate Student- Role of Angiotension 1-7 in the development of cardiovascular fibrosis.

July 2009

• July 1 - Carmen De Miguel, Graduate Student- The role of renal immune cell infiltration in salt-sensitive hypertension.
• July 8 - Caitlin O' Meara, Graduate Student- The genetics of renal failure in the Fawn Hooded Hypertensive rat.
• July 13- Josh Bonis- Dissertation Defense- Insights into the role of pontine respiratory group in the control of breathing during physiologic conditions.
• July 15 - Di (Raina) Feng, Graduate Student- Role of p67 in the development of Salt-sensitive hypertension in Dahl S rats.
• July 22 - Sarah Parker, Graduate Student- Therapeutic efficacy of bone marrow derived progenitor cells during heart failure in the Dahl salt-sensitive rat.
• July 29 - Pallabi Sarkar, Graduate Student- Cytoprotective effect of EETs in brain.

June 2009

• June   3  -  Filip Sedlic, Graduate Student - Reactive oxygen species and mitochondria in anesthetic preconditioning
• June   5   - Gerald B. Spurr Memorial - Julio Reina, M.D. - Malnutrition, work capacity, and productivity
• June 10  -  Matthew Durand, Graduate Student - A congenic approach to understanding endothelial dysfunction in the cerebral circulation of  the Dahl SS rat
• June 17 -   Amy Cayemberg, Graduate Student - The effects of ROCK isoform knockdown on fibroblast contractility
• June 24  -  Edward Frohlich, M.D. - The role of salt in hypertension - it doesn't only raise blood pressure

May 2009

• May  7  -  Doris A. Taylor, Ph.D. - Cells for Prevention, Treatment and Cure of Cardiovascular Disease
• May 13  - CANCELLED
• May 20  -  Howard Jacob, Ph.D. - The changing landscape of animal models: Back to the future
• May 27  -  CANCELLED

April 2009

• April   1   -  Catherine Kaczorowski, Ph.D. - Plasticity of Intrinsic Excitability in learning and Aging
• April   2  -   Lucas Hart - Dissertation Defense - The effect of motor learning on protein expression and functional hyperemia in the cerebral cortex
• April   8  -  James Amos-Landgraf, Ph.D. - Building a better model of human colon cancer.  The development of the Pirc rat for genetics, genomics                    and toxicogenomics of tumor development and response
• April 15  -  Paula North, MD, Ph.D. - The life of an endothelial cell in infantile hemangioma: a story of proliferation, senescence, and death
• April 22  -  No Seminar
• April 29  -  Carlos Schreck, MD - Dilutional fluorescent method to measure glomerular albumin reflection coefficient in vitro

March 2009

• March  4   -  Cheryl Stucky, Ph.D. - TBA
• March 11  -   Aron Geurts, Ph.D. - That was yesterday, this is tomorrow - manipulating the rat genome to build the next generation of disease models
• March 18  -  Jeffery D. Molkentin, Ph.D. - Genetic dissection of MAPK signaling pathways in cardiac hypertrophy
• March 25  -  Kathryn LaNoue, Ph.D. - Glutamate metabolism in the brain, "What could go wrong?"
• March 30  -  Aaron Polichnowski - Dissertation Defense - Mechanisms of hypertension-induced renal injury
• March 31  -  Talha Akbulut - Dissertation Defense - Protective role of 20-HETE against renal ischemia and reperfusion injury

February 2009

• Feb.  4   -  Richard Roman, Ph.D. - Use of Consomic and Congenic strains of rats for dissecting the genetic basis of hypertension and renal disease
• Feb. 11  -   Ramani Ramchandran, Ph.D. - Navigation of Vessels: Lessons Learned from Axon Guidance
• Feb. 18  -  Michael Widlansky, M.D. - Mitochondrial Homeostasis and Vascular Endothelial Dysfunction in Diabetes
• Feb. 25  -  Paul O'Connor, Ph.D. - Identifying the source of oxidative stress in the salt-sensitive kidney

January 2009

• Jan. 7   -  Tetsuro Wakatsuki, Ph.D. - Engineered tissue based high-throughput functional genomic analysis
• Jan. 14 -   Hartmut Weiler, Ph.D. - Innate immunity and the blood coagulation syster
• Jan. 21 -  Hubert (Bert) Forster, Ph.D. - What stimulates breathing: rest, (awake and asleep) and exercise?
• Jan. 23 -  Ryan D. Schulteis - Master's Thesis Defense - Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking gimap5
• Jan. 28 -  Melinda Dwinell, Ph.D. - Phenotypes and disease models: lessons from the PGA

December 2008

• Dec. 3   -  Dissertation Defense - Daniel Brozoski, Grad Student - Effects of endocannbinoids in the central control of the baroreflex in hypertensive and normotensive rats
• Dec. 10 -   Cancelled
• Dec. 17 -  Andrew Tryba, Ph.D. - TRPing over your next breath & the role of neuromodulators in rhythm generation during breathing and seizing
• Dec. 24 -  No Seminar
• Dec. 31 -  No Seminar

November 2008

• Nov. 5   -  Nashaat Gerges, Ph.D. - Role of neurogranin in synaptic plasticity balance
• Nov. 12 -   Mingyu Liang, MB, Ph.D. - MicroRNA and systems molecular medicine
• Nov. 19 -  Toku Takahashi, MD, Ph.D. - Effects of acute and chronic stress on gastric motor function
• Nov. 26 -  No Seminar

October 2008

• Oct. 1 -    Frans Leenen, M.D., Ph.D. - The brain and salt-sensitive hypertension
• Oct. 8 -   Anthony G. Hudetz, Ph.D. - Neural correlates of anesthesia??
• Oct. 15 -  Lisamarie Collins - A proteomic approach to identify candidate genes influencing HDL particle size in obesity
• Oct. 22 -  Hershel Raff, Ph.D. - Cushing' Syndrome: From basic physiology to diagnosis and differential diagnosis
• Oct. 29 -  Talha Akbulut - The role of 20-HETE in ischemia and reperfusion injury

September 2008

• Sept. 3 -    Alan Sinaiko, MD - Insulin resistance vs. BMI in the development of cardiovascular risk
• Sept. 10 -  Carmane De Miguel - Renal infiltration of immune cells and hypertension
• Sept. 17 -  Satarupa Das - The effects of L-Arginine on Angiotensin-II infused hypertensive rats
• Sept. 24 -  Debebe Gebremedhin, Ph.D. - Oxidant modulation of mechanisms regulating cerebral vascular function
• Sept. 25 -  Simon Malpas, Ph.D. - The role of the sympathetic nervous system in the development of cardiovascular disease

August 2008

• Aug. 6 -  Graduate Students Retreat Day
• Aug. 13 -  Amy Cayemberg - The role of Rho Kinase in fibroblast contraction and cardiac fibrosis
• Aug. 15 - James R. Schmidt, Dissertation Defense - The role of the renin angiotensin system in the control of blood flow in the rat
• Aug. 20 - Matthew Durand - Regulatin of the renin gene and its role in maintaining normal vascular relaxation mechanisms
• Aug. 27 - Di Feng - Determination of the role of p67 in the development of salt-sensitive Dahl S rats
• Aug. 27 - Sarah Parker - Techniques for the relative quantitation of proteins involved in angiogenesis

July 2008

• July  2 -  Michael Michalkiewicz, Ph.D. - Epigenetics of hypertension and renal disease
• July  9 -  Aaron Polichnowski - Mechanisms of renal injury in hypertensive models with altered angiotensin II and Nitric Oxide
• July 16 - James Stockand, Ph.D. - Hypertension in P2Y2 receptor-deficient mice is caused by constitutive activation of ENaC
• July 23 - Allen W. Cowley, Jr., Ph.D. - Mechanisms of renal medullary oxidative stress in salt-sensitive hypertension
• July 30 - Lucas Hart - Cerebral cortex blood flow responses in skilled behavior and motor learning

June 2008

• June  4 -  Daniel Brozoski - The role of endocannabinoids in the central control of the baroreflex in hypertensive and normotensive rats
• June 11 - Ashraf El-Meanawy M.D., Ph.D. - Oligonephronia in the Oligosyndactyly mouse
• June 18 - No Seminar
• June 25 - Josh Bonis - Modulation of the pontine respiratory group alters breathing and sleep

May 2008

• May  7 -  Diane Munzenmaier, Ph.D. - Angiotensins and vascular growth: the controversy continues
• May 12 - JJ Smith Lecture, Dr. Eric O. Feigl - Control of coronary blood flow during exercise (Why we don't die when we walk up the stairs)
• May 14 - Ronald M. Harper, Ph.D. - Imaging of brain structure in sleep-disordered breathing
• May 20 - Master's Thesis, Matthew Brown - Vascular remodeling in a rat model of unilateral pulmonary artery hypoplasia
• May 21 - Jordan Miller, Ph.D. - Oxidative stress in calcific aortic valvular stenosis
• May 27 - Dissertation Defense, Alison Kriegel - Substitution of Brown Norway chromosome 16 preserves cardiac function with aging in a salt-sensitive Dahl consomic rat
• May 28 - Ellis Avner, M.D. - New insights into cellular pathophysiology of polycystic kidney disease

April 2008

• April  2 -  Jan Williams, Ph.D. - The progression of renal disease in the Dahl S rat vs. the FHH rat: Who's your money on?
• April  9 -  No Seminar
• April 14 - Nader Abraham, Ph.D. - Functional expression of heme oxygenase-stem cells in obesity and metabolic syndrome
• April 15 - Peter Hunter, Ph.D., FRS - Multi-scale modeling and computational physiology
• April 16 - Michael Harrison, Dissertation Defense - The comparative genetics of Phosducin, a novel candidate gene for hypertension
• April 17 - Lutz Hein, MD - Adrenergic signaling at the interface between neuronal and cardiovascular systems
• April 23 - Robin L. Davisson, Ph.D. - Student Choice Speaker - Physiological genomic analysis of cardiovascular disease
• April 30 - David Harder, Ph.D. - To Be Announced

March 2008

• March  4 -  Raymond C. Koehler, Ph.D. - Mechanisms of neurovascular coupling
• March  5 -  Kathryn Dunn, Dissertation Defense - The role of 20-HETE in ischemic stroke sensitivity and cerebral vascular oxidative stress in spontaneous hypertension
• March 12 - Simon Twigger, Ph.D. - Seven bioinformatics secrets you need to know
• March 19 - Katie Krause, Dissertation Defense - The role of the pre-Botzinger Complex in respiratory rhythmogenesis and chemosensitivity during physiologic conditions
• March 26 - Alexander Starushchenko, Ph.D. - Acute regulation of the Epithelial Na+ Channel by P13-kinase signaling

February 2008

• Feb.  6 -  Anthony Hudetz, DBM, Ph.D. - Neural correlates of anesthesia
• Feb. 13 - Gabor Raffai, Ph.D. - Adaptation of the cardiovasculary system to gravitational loading: systemic hemodynamic and regional vascular responses to acute and chronic orthostasis
• Feb. 20 - Jeanne Seagard, Ph.D. - Endocannabinoid modulation of baroreflex control
• Feb. 27 - Kirk Pritchard, Ph.D. - Matrix instability and impaired angiogenesis in tight skin mice - a murine model for systemic sclerosis

January 2008

• Jan.  2 -  No Seminar
• Jan.  9 -  Philip Clifford, Ph.D. - Reedforward skeletal muscle vasodilation at the onset of exercise.
• Jan. 16 - Daniel Beard, Ph.D. - Simulation and analysis of coronary oxygen transport and cardiac energy metabolism.
• Jan. 23 - David Rector, Ph.D. - High frequency oscillations (200-600Hz) and their role in sensory processing.
• Jan. 30 - David Mattson, Ph.D. - Protein-sensitive hypertension and renal disease in Dahl SS rats.

December 2007

• Dec. 5     -  No Seminar
• Dec. 12   -  Zeljko Bosnjak, Ph.D. - Protection against ischemia and reperfusion injury
• Dec. 19   -  Yong Liu, Ph.D. - 11B-hydroxysteroid dehydrogenase 1: from adipogenesis to salt-sensitive hypertension
• Dec. 26   -  No Seminar

November 2007

• Nov. 7     -  Julie Freed, Disseration Defense - Proteomic analysis of shear stress-mediated protection from apoptosis in endothelial cells
• Nov. 14   -  Paul O'Connor, Ph.D. - Oxidative stress in the renal medulla of salt-sensitive rats
• Nov. 21   -  Thanksgiving Week - No Seminar
• Nov. 27  -   Kelly Duffy, Dissertation Defense - Functional genetic analysis of pathogenic chromosomal copy number variation in Down syndrome and Proteus syndrome
• Nov. 28   -  Bradford C. Berk, MD, Ph.D. - Genetics of vascular remodeling

October 2007

• Oct. 3    -  Andrew S. Greene, Ph.D. - Recent progress in the Greene Lab
• Oct. 10  -  Marc Chevalier, Ph.D. - Body rhythms linked to ion channel activity: focus on epilepsy disorders
• Oct. 17  -  Jean F. Liard, MD, Ph.D. - Bumps on the translational highway
• Oct. 24  -  Satarupa Das, Grad Student - Role of immune cells in the development of hypertension and kidney disease
•                  Carmen De Miguel, Grad Student - Effects of L-Arginine infusion on Angiotensin II-induced hypertension
• Oct. 31  -  Howard Jacob, Ph.D. - Linking the Framingham Heart Study to the Program in Genomic Applications

September 2007

• Sept. 12  -  Hartmut Weiler, Ph.D. - Protein C Pathway in the Treatment and Pathogenesis of Sepsis
• Sept. 19 -  Lucas Hart - The role of the neurovascular unit in learning
• Sept. 26 -  Michael Olivier, Ph.D. - Human functional Disease Genetics: The trials and Tribulations of NOT Working with Rats

August 2007

• Aug. 1   -  Allen Cowley, Jr. - Hypertension and pressure-natriuresis in theory and practice
• Aug. 8   -  Graduate Student Retreat
• Aug. 15 -  Aaron Polichnowski - Hypertension-induced renal damage
• Aug. 22 -  Daniel Brozoski - The role of endocannabinoids in the central control of the baroreflex
• Aug. 29 -  Domagoj Mladinov - Further understanding the mechanism of hypertension - analysis of eNOS promoter
• Aug. 29 -  Talha Akbulut - The role of cytochrome P450 following ischemia-reperfusion injury in the rat kidney

July 2007

• July 4  - Holiday
• July 11 - Josh Bonis - The pons: where do we go, how do we get there, and what does it do for breathing
• July 20 - Steven R. Goldsmith, MD - Vasopressin antagonism in heart failure and hyponatremia: theory and current practice
• July 25 - Alison Kriegel - Characterization of idiopathic left ventricular hypertrophy and impaired cardiac function in the SS-16BN/Mcwi consomic rat

June 2007

• June 6  - Kelly Duffy - Somatic partial chromosome 11 duplication in patients with Proteus syndrome
• June 14 - Kimberly Pechman, Dissertation Defense - The long term effects of altered structure and function following acute renal failure
• June 20 - Katie Dunn - The role of 20-HETE in ischemic stroke and cerebral vascular dysfunction in the stroke prone rat
• June 27- Katie Krause - The pre-Botzinger complex may not be the sole determinant of respiratory rhythm

May 2007

• May 2   - No Seminar
• May 9   - Mingyu Liang, Ph.D. - MicroRNA
• May 16 - Thomas Feroah, Ph.D. - Assessing novel and circadian movement behavior in parental and ENU knockout inbred strains of rats
• May 23 - Edward Smith, Ph.D. - Fine-mapping a human QTL associated with the lipid profile
• May 30 - Tetsuro Wakatsuki, Ph.D. - To Be Determined

April 2007

• April 4   - Xujing Wang, Ph.D. - Network modeling of gene expression data
• April 11 - Hubert Forster, Ph.D. - Muscle activation patterns and neural mechanisms regulating multiple behaviors utilizing the respiratory muscles
• April 18 - Michael Michalkiewicz, DVM, Ph.D. - Validation of a candidate disease gene with inclusion of epigenomic tools
• April 24 - Jeffrey Eckert, Grad Student Dissertation Defense - The role of protein tyrosine phosphatase 1 beta sequence variants in human obesity
• April 25 - Donald Bowden, Ph.D. - Genetics studies of diabetes, metabolic dysregulation, and their complications in diverse human populations
• April 26 - Kevin Campbell, Ph.D. - Student Choice Seminar - Maintenance of cell membrane integrity and the pathogenesis of muscular dystrophy, 3:30 HRC Auditorium

March 2007

• March 7 - Andrew Tryba, Ph.D. - Mechanisms of rhythm generation in neocortical epilepsy
• March 14 - Melinda Dwinell, Ph.D. - Who's on first? Deciphering chromosome1 using consomic rats
• March 21 - Scott McEwen, Grad Student Dissertation Defense - The role of AT-1 receptor signaling to restore cerebrovascular relaxation mechanisms
• March 22 - Abraham P. Provoost, Ph.D. - Physiological genomics of renal damage and blood pressure in the FHH rat
• March 29 - Jasna Marinovic, Grad Student Dissertation Defense - The role of sarcolemmal KATP channel in cardiac preconditioning and apoptosis
• March 30 - Marko Ljubkovic, Grad Student Dissertation Defense - Cardiomyocyte resistance to injury can be enhanced by modulation of mitochondrial K+ homeostasis

February 2007

Note Thursday Seminar

• Feb. 7 - Frank Park, Ph.D. - The nuts and bolts about lentiviral vectors
• Feb. 14 - Rajesh Khanna, Ph.D. - Ion channel trafficking: from molecule to malady
• Feb. 22 - Michael Garrett, Ph.D. - Searching for the molecular basis of renal disease in the Dahl salt-sensitive rat: linkage analysis, congenic strains, and fine-mapping using recombinant progeny testing
• Feb. 28 - Kalyan Vinnakota, Ph.D. - pH dynamics, glycogenolysis and phosphoenergetics in isolated cell free reconstituted systems and in mouse skeletal muscle

January 2007

• Jan. 3  -  No Seminar
• Jan. 10 - Julian Lombard, Ph.D. - Role of Angiotensin II in regulating vascular relaxation mechanisms: more new verses to an old song
• Jan. 17 - No Seminar
• Jan. 24 - Simon Twigger, Ph.D. - Annotating the List - bioinformatic approaches to experimental data annotation
• Jan. 31 - Tatjana Adamovic, Ph.D. - Identification and characterization of cancer genes in hormone-dependent tumors: molecular genetic analysis  in rat models of endometrial and mammary cancer